Advanced kidney technology now available to Filipinos

0
Albert Poblete, division vice president-general manager of Biomedis Inc., unveils the breakthrough technology of potassium citrate during the simultaneous symposium held in Manila, Tagaytay and Cebu

Albert Poblete, division vice president-general manager of Biomedis Inc., unveils the breakthrough technology of potassium citrate during the simultaneous symposium held in Manila, Tagaytay and Cebu

The  just concluded Tascit Sci-Tech Summit titled “Cutting Edge,” unveiled the advanced technology in kidney stone management and the pioneering research and development (R&D) behind Biomedis’ potassium citrate (Tascit). It was the first of its kind in the pharmaceutical and medical sector.

“As the makers of extended-release potassium citrate (Tascit) tablets, it is our commitment to make use of technology in a way that would be most helpful to our partners in the medical community and most advantageous to the Filipino patient. This is why we wanted to share with you the exciting story behind our product with the aid of advance technology,” said Albert Poblete, General Manager of Biomedis Inc., a division of Unilab.

Doctors were presented with high-tech presentations using holograms of Unilab Senior Vice President for R&D, Dr. Kennie Dee, and Dr. Dennis Serrano. Dr. Kennie Dee has a PhD in Chemical Engineering from Cornell University while Dr. Serrano is an active consultant in Urology and Kidney Transplantation at St. Luke’s Medical Center Global, National Kidney Institute and Asian Hospital.

Resource speakers Dr. Dennis Serrano and Dr. Kennie Dee

Resource speakers Dr. Dennis Serrano and Dr. Kennie Dee

The hologram presentation is a  feature of the summit attended by over 1,500 doctors. This technology enabled the event to be beamed simultaneously to three locations: SMX Aura Convention Center in Taguig, Robinsons Summit Ridge Hotel in Tagaytay City and Marco Polo Hotel in Cebu.


Dr. Serrano discussed the history, statistics and technology involved in kidney stones management. According to him, an estimated 10 percent of all people will have a kidney stone at some point in their lives, with peak incidence rising between the ages of 20 to 40 years old.

“Beating stone disease is indeed a challenge, but it is a challenge that we can measure up through dietary manipulation, lifestyle changes, paying attention to adequate hydration day in and day out, and recognition of the importance of inhibitory substances in the prevention of stone formation,” he cited.

He emphasized the use of potassium citrate for inhibition of growth and aggregation of calcium phosphate crystals, and for the treatment of uric acid stones that may occur concurrently with or without calcium stones.

Potassium citrate can also be used to prevent the recurrence of calcium oxalate and uric acid stones, which comprise about 85 percent to 90 percent of kidney stones.

According to Dr. Serrano, what is needed is a formulation that is stable enough for constant controlled release and friendly to the gastrointestinal tract. And this, Dr. Dee cited, is why Biomedis came up with potassium citrate wax matrix extended release potassium citrate tablets.

Dr. Dee demonstrated how the potassium citrate particles in Tascit are entrapped in a waxy matrix, and then slowly released from the wax tablet. Since waxes are insoluble, the wax matrix tablet remains intact as it passes through the gastro-intestinal tract.

“Some generics that tried to enter the US market have repeatedly been recalled because of failure to meet the critical dissolution specifications set by United States Pharmacopeia (USP),” cited Dr. Dee
USP dissolution requirements ensure that the potassium citrate is released from the tablet gradually to allow a constant level of citrate excretion over an extended period as compared to immediate release formulations.

Unilab’s R&D head said their scientists quickly succeeded in making Tascit wax matrix tablet’s small-scale trials compliant with the USP dissolution specifications.

Biomedis’ Tascit (potassium citrate ER) is classified by the USFDA as a GRAS material, which stands for “Generally Regarded as Safe.” A GRAS classification means that Potassium Citrate can do no harm to humans if used in reasonable amounts.

“It is a challenge that I have no doubt we can conquer so that fewer patients will need to undergo surgery, fewer patients will suffer chronic kidney disease, fewer patients will have acute stone episodes and many more will have no stone recurrences,” Dr. Serrano ended.

Share.
.
Loading...

Please follow our commenting guidelines.

Comments are closed.