American housewife Nancy Kissel, dubbed the "milkshake murderer", on Tuesday lost an appeal against her second conviction in Hong Kong for the 2003 murder of her banker husband.

The 49-year-old expatriate, serving a life sentence since 2005, was found guilty of drugging her husband—a senior executive at US bank Merrill Lynch—with a sedative-laced strawberry drink before clubbing him to death with a lead ornament in their luxury home.

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