• Iran, Singapore produce artificial skin


    TEHRAN: Iranian researchers at Isfahan University of Technology, in association with their counterparts at the National University of Singapore, have developed nanofibrous gelatin skin for wound treatment.

    Elham Vatankhah, a PhD student of Isfahan University of Technology in textile engineering and the project researcher, said the biodegradable nanofiber has been created from cellulose acetate/gelatin and it is an effective simulator of the structure and composition of native skin, Iran Daily wrote in its Monday edition.

    ˈWe electrospun cellulose acetate/gelatin membranes in various compositions and evaluated their performance as a scaffold for skin tissue engineering and wound dressing,ˈ she said.

    The expert noted that tissue-engineered scaffolds and wound dressings should be hydrophilic to allow oxygen and fluid exchange, and absorb excess exudates.

    Vatankhah explained that a wound dressing should be easily removed without causing tissue damage and a tissue-engineered scaffold should be able to adhere to the wound and support cell proliferation during skin regeneration.

    ˈWe changed the composition of cellulose acetate and gelatin in composite cellulose acetate/gelatin scaffolds and found that increasing the amount of gelatin will increase the adhesion properties of the nanofiber,ˈ she said.

    Electrospun cellulose acetate/gelatin (25/75) nanofibers can be a potential tissue-engineered scaffold and the 75/25 can be a potential low-adherent wound dressing.

    Electrospinning uses an electrical charge to draw very fine (typically on the micro or nano scale) fibers from a liquid.

    Dermal fibroblasts are cells within the dermis layer of skin, which are responsible for generating connective tissue and allowing the skin to recover from injury. PNA


    Please follow our commenting guidelines.

    Comments are closed.