Shaina Magdayao (right) and Gerald Anderson return to the prime time block with first timer Isabelle Daza
Completing the powerhouse cast of Nathaniel are Pokwang, Isabelle Daza, Benjie Paras, Jayson Gainza, Ogie Diaz, Sharlene San Pedro, Jairus Aquino, Yesha Camile, David Chua, Young JV, Fourth and Fifth Pagotan, and veteran actress Coney Reyes. It directed by Darnel Joy Villaflor and Francis Pasion.