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Wednesday, March 19, 2008

 

Genetic links to disease spur hope for cure

 
CHICAGO: An explosion in genetic research is helping physicians detect and treat deadly diseases and could soon lead to genetic prescreening to assess risk and design personalized preventative treatments, researchers said Tuesday.

A special issue of the Journal of the American Medical Association assessed the state of genetic-based treatments and presented a number of significant discoveries, including a genetic predisposition for developing post-traumatic stress disorder.

“The magnitude, scope, and pace of discovery in genetics and genomics research are at unprecedented levels and continue to increase exponentially,” JAMA editor in chief Catherine DeAngelis wrote in a co-authored editorial.

“These discoveries have important implications for understanding disease processes, for predicting disease susceptibility and progression, and for refining and individualizing treatments—all of which ultimately have the potential to improve health and to increase both quality of life and longevity.”

Advanced computing technology and the completion of the Human Genome Project in 2003 and other key databases have pushed genetic research into “a rapid discovery phase,” lead author Gregory Feero of the National Human Genome Research Institute wrote in a commentary.

“In the past year, genome-wide association studies yielded highly robust information on scores of new genetic markers for common chronic disorders including diabetes, heart disease, Crohn disease, and several common cancers,” he wrote.
-- AFP

   

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