KABUL, Afghanistan: A powerful earthquake struck a rural, mountainous region of eastern Afghanistan early Wednesday, killing 1,000 people and injuring 1,500 more in one of the deadliest temblors in decades, the state-run news agency reported. Officials warned that the already grim toll may still rise.

Information remained scarce on the magnitude 6.1 temblor near the Pakistani border, but quakes of that strength can cause severe damage in an area where homes and other buildings are poorly constructed and landslides are common. Experts put the depth at just 10 kilometers (6 miles) — another factor that could lead to severe destruction.

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